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CD3 epsilon Antikörper (Cytoplasmic Domain)
CD3E
Reaktivität: Human, Maus, Schwein, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen
FACS, WB, IF, IHC (p)
Wirt: Maus
Monoclonal
PC3-188A
unconjugated
Produktnummer ABIN6252415
Produktdetails anti-CD3 epsilon Antikörper
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Target
Alle CD3 epsilon (CD3E) Antikörper anzeigen
CD3 epsilon (CD3E)
Bindungsspezifität
Alle Epitope für CD3 epsilon Antikörper
AA 156-168, Cytoplasmic Domain
Reaktivität
Alle Reaktivitäten für CD3 epsilon Antikörper
Human, Maus, Schwein, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen
Wirt
Alle Wirte für CD3 epsilon Antikörper
Maus
Klonalität
Alle Klonalitäten für CD3 epsilon Antikörper
Monoklonal
Konjugat
Alle Konjugate für CD3 epsilon Antikörper
Dieser CD3 epsilon Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CD3 epsilon Antikörper
Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
Protein G affinity chromatography
Immunogen
Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.
Klon
PC3-188A
Isotyp
IgG1
Top Product
Discover our top product CD3E Primärantikörper
Alternativen
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anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E
Reaktivität: Human, Schwein, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Huhn
FACS, WB, IF
Wirt: Maus
Monoclonal
PC3-188A
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB: 1-2 μg/mL IHC (FFPE): 1-2 μg/mL for 30 min at RT Flow Cytometry: 0.5-1 μg/million cells in 0.1ml Immunofluorescence: 1-2 μg/mL Optimal dilution of the CD3e antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Details zu CD3 epsilon
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Target
CD3 epsilon (CD3E)
Andere Bezeichnung
CD3e (CD3E Produkte )
Synonyme
cd3e antikoerper, CD3E antikoerper, t3e antikoerper, tcre antikoerper, AI504783 antikoerper, CD3 antikoerper, CD3epsilon antikoerper, T3e antikoerper, T3E antikoerper, TCRE antikoerper, CD3e molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, cd3e antikoerper, CD3E antikoerper, Cd3e antikoerper
Hintergrund
Recognizes the epsilon chain of CD3, a protein which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Gen-ID
916
UniProt
P07766
Pathways
T-Zell Rezeptor Signalweg , CXCR4-mediated Signaling Events , Ubiquitin Proteasome Pathway
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