IFNA2 Antikörper

Produktnummer ABIN6252255

Dieser Maus Monoklonal Antikörper detektiert spezifisch IFNA2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IFNA2 Antikörper (ABIN6252255)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: N39

Produktdetails anti-IFNA2 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: ELISA: order BSA/azide-free format for coating

Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Andere Bezeichnung: Interferon alpha 2

Hintergrund: Recognizes a protein of 16-27  kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Gen-ID: 3440

UniProt: P01563

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C