MMP2 Antikörper (AA 195-319)
Kurzübersicht für MMP2 Antikörper (AA 195-319) (ABIN6252229)
Target
Alle MMP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 195-319
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Amino acids 195-319 were used as the immunogen for the MMP2 antibody.
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Isotyp
- IgG1
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Applikationshinweise
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WB: 0.5-1 μg/mL
The stated application concentrations are suggested starting amounts. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Andere Bezeichnung
- MMP2
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Hintergrund
- It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.
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Gen-ID
- 4313
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UniProt
- P08253
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Pathways
- Activation of Innate immune Response
Target
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