Podoplanin Antikörper (AA 24-126)

Produktnummer ABIN6252118

Der Maus Monoklonal anti-Podoplanin Antikörper wird verwendet zum Nachweis von Podoplanin in Proben von Human. Er wurde validiert für WB, FACS, IF und IHC (p).

Kurzübersicht für Podoplanin Antikörper (AA 24-126) (ABIN6252118)

Target: Podoplanin (PDPN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Podoplanin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PDPN-1433

Produktdetails anti-Podoplanin Antikörper

Bindungsspezifität: AA 24-126

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL

IF: 0.5-1 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu Podoplanin

Target: Podoplanin (PDPN)

Andere Bezeichnung: Podoplanin

Hintergrund: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

Gen-ID: 10630

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport