CD2 Antikörper

Produktnummer ABIN6251870

Dieser Anti-CD2 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD2 in FACS, IF, WB und Func. Geeignet für Human und Cat.

Kurzübersicht für CD2 Antikörper (ABIN6251870)

Target: CD2

Reaktivität: Human, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Klon: HuLy-m1

Produktdetails anti-CD2 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Human thymocytes were used as the immunogen for the CD2 antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Functional Activity (Order SAF formulation)

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Western blot: 1-2 μg/mL

Optimal dilution of the CD2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Gen-ID: 914

UniProt: P06729