SIX Homeobox 1 Antikörper (AA 69-102)
Kurzübersicht für SIX Homeobox 1 Antikörper (AA 69-102) (ABIN6244222)
Target
Alle SIX Homeobox 1 (SIX1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 69-102
-
Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This SIX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 69-102 amino acids from the Central region of human SIX1.
-
Isotyp
- Ig Fraction
-
-
anti-SIX Homeobox 1 (SIX1) antibody
SIX1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (Middle Region) antibodySIX1 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 144-262) antibodySIX1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 60-270) antibodySIX1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 1-284) antibodySIX1 Reaktivität: Human ELISA Wirt: Maus Monoclonal 3C7 unconjugated
anti-SIX Homeobox 1 (SIX1) (C-Term) antibodySIX1 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Schwein, Fledermaus, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (Internal Region) antibodySIX1 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (N-Term) antibodySIX1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (N-Term) antibodySIX1 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- WB: 1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Haltbarkeit
- 6 months
-
-
- SIX Homeobox 1 (SIX1)
-
Andere Bezeichnung
- SIX1
-
Hintergrund
- Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.
-
Molekulargewicht
- 32210
-
UniProt
- Q15475
-
Pathways
- Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
-
