SIX Homeobox 1 Antikörper (Middle Region)

Produktnummer ABIN2779599

Produktdetails anti-SIX Homeobox 1 Antikörper

Target: SIX Homeobox 1 (SIX1)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIX Homeobox 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SEEEFSPPQS PDQNSVLLLQ GNMGHARSSN YSLPGLTASQ PSHGLQTHQH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 284 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SIX Homeobox 1 Antikörper (ABIN2779599)

Lee, Kim, Ryu, Lee, Yang, Jeong, Kim, Lee, Kim, Hajjar, Park: "Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 3, pp. 718-26, (2012) (PubMed).

Details zu SIX Homeobox 1

Target: SIX Homeobox 1 (SIX1)

Andere Bezeichnung: SIX1 (SIX1 Produkte)

Synonyme: BOS3 antikoerper, DFNA23 antikoerper, TIP39 antikoerper, BB138287 antikoerper, six1b antikoerper, six2 antikoerper, zgc:92332 antikoerper, XSix1 antikoerper, six1 antikoerper, zgc:77345 antikoerper, SIX homeobox 1 antikoerper, sine oculis-related homeobox 1 antikoerper, SIX homeobox 1a antikoerper, SIX homeobox 1 L homeolog antikoerper, SIX homeobox 1b antikoerper, SIX1 antikoerper, Six1 antikoerper, six1a antikoerper, six1.L antikoerper, six1b antikoerper

Hintergrund: SIX1 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BOS3, DFNA23, TIP39
Protein Interaction Partner: AES, VTN, FZR1, UBC, SKI, CCDC85B, DACH1, EYA3, EYA2, MDFI, EYA4, EYA1, SIX1, TLE1,
Protein Size: 284

Molekulargewicht: 32 kDa

Gen-ID: 6495

NCBI Accession: NM_005982, NP_005973

UniProt: Q15475

Pathways: Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development