VANGL2 Antikörper (AA 376-410)
Kurzübersicht für VANGL2 Antikörper (AA 376-410) (ABIN6244034)
Target
Alle VANGL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 376-410
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This VANGL2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-410 amino acids from human VANGL2.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- VANGL2 (Vang-Like 2 (VANGL2))
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Andere Bezeichnung
- VANGL2
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Hintergrund
- Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
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Molekulargewicht
- 59714
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UniProt
- Q9ULK5
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Pathways
- WNT Signalweg, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization
Target
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