IFT57 Antikörper (AA 159-193)
-
- Target Alle IFT57 Antikörper anzeigen
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
-
Bindungsspezifität
- AA 159-193
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IFT57 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Homologie
- B
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This IFT57 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 159-193 amino acids from the Central region of human IFT57.
- Klon
- RB57869
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IFT57 Primärantikörper
-
-
- Applikationshinweise
- WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
-
- Target
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
- Andere Bezeichnung
- IFT57 (IFT57 Produkte)
- Hintergrund
- Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
- Molekulargewicht
- 49108
- UniProt
- Q9NWB7
- Pathways
- Hedgehog Signalweg, Positive Regulation of Endopeptidase Activity
-