SFRP2 Antikörper (C-Term)

Produktnummer ABIN6243546

Der Kaninchen Polyklonal Anti-SFRP2-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, SFRP2 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für SFRP2 Antikörper (C-Term) (ABIN6243546)

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB31048

Produktdetails anti-SFRP2 Antikörper

Bindungsspezifität: AA 263-292, C-Term

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SFRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human SFRP2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SFRP2 Antikörper (ABIN6243546)

Higgins, Chen, Cerise, Jahoda, Christiano: "Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 49, pp. 19679-88, (2014) (PubMed).

Details zu SFRP2

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Andere Bezeichnung: SFRP2

Hintergrund: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq].

Molekulargewicht: 33490

NCBI Accession: NP_003004

UniProt: Q96HF1

Pathways: WNT Signalweg, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation