ALK Antikörper (AA 636-666)

Produktnummer ABIN6243477

Der Kaninchen Polyklonal anti-ALK Antikörper wird verwendet zum Nachweis von ALK in Proben von Human. Er wurde validiert für IHC (p) und WB.

Kurzübersicht für ALK Antikörper (AA 636-666) (ABIN6243477)

Target: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALK Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Klon: RB15425

Produktdetails anti-ALK Antikörper

Bindungsspezifität: AA 636-666

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-666 amino acids from the Central region of human ALK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu ALK

Target: ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))

Andere Bezeichnung: ALK

Hintergrund: ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.

Molekulargewicht: 176442

NCBI Accession: NP_004295

UniProt: Q9UM73

Pathways: RTK Signalweg