CBX7 Antikörper (C-Term)

Produktnummer ABIN6243433

Dieses Anti-CBX7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CBX7 in WB. Geeignet für Human.

Kurzübersicht für CBX7 Antikörper (C-Term) (ABIN6243433)

Target: CBX7 (Chromobox Homolog 7 (CBX7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB51547

Produktdetails anti-CBX7 Antikörper

Bindungsspezifität: AA 168-201, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CBX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-201 amino acids from the C-terminal region of human CBX7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu CBX7

Target: CBX7 (Chromobox Homolog 7 (CBX7))

Andere Bezeichnung: CBX7

Hintergrund: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

Molekulargewicht: 28341

UniProt: O95931