UHMK1 Antikörper (C-Term)

Produktnummer ABIN6243411

Der Kaninchen Polyklonal Anti-UHMK1-Antikörper wurde für WB validiert. Er ist geeignet, UHMK1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für UHMK1 Antikörper (C-Term) (ABIN6243411)

Target: UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UHMK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB5431

Produktdetails anti-UHMK1 Antikörper

Bindungsspezifität: AA 265-295, C-Term

Homologie: Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-295 amino acids from the C-terminal region of human KIST (KIS).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu UHMK1

Target: UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Andere Bezeichnung: KIST (KIS)

Hintergrund: KIST, a member of the Ser/Thr protein kinase family, is a pyruvate kinase that catalyzes formation of phosphoenolpyruvate from pyruvate and ATP. A role for the primarily nuclear KIST protein in mediation of cellular metabolism has been postulated based on the interaction identified with thyroid hormone. KIST is widely expressed, with highest abundance in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Upon serum stimulation, KIST phosphorylates CDKN1B/p27Kip1, thereby regulating the subcellular location of CDKN1B and cell cycle progression in the G1 phase. KIST, which contains one RNA recognition motif domain, has been proposed to partipate in trafficking and processing of RNA. KIST binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells.

Molekulargewicht: 46546

NCBI Accession: NP_001171692, NP_653225, NP_787062

UniProt: Q8TAS1