SLC7A8 Antikörper (AA 476-506)

Produktnummer ABIN6243302

Produktdetails anti-SLC7A8 Antikörper

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Bindungsspezifität: AA 476-506

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC7A8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC7A8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 476-506 amino acids from human SLC7A8.

Klon: RB55244

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:2000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SLC7A8

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Andere Bezeichnung: SLC7A8 (SLC7A8 Produkte)

Synonyme: LAT2 antikoerper, LPI-PC1 antikoerper, Lat2 antikoerper, Lat4 antikoerper, XAA2 antikoerper, lat2 antikoerper, lpi-pc1 antikoerper, 4F2LC-5 antikoerper, AA408822 antikoerper, si:ch211-14a17.3 antikoerper, si:zc14a17.3 antikoerper, slc7a8 antikoerper, solute carrier family 7 member 8 antikoerper, solute carrier family 7 member 8 L homeolog antikoerper, solute carrier family 7 (amino acid transporter, L-type), member 8 antikoerper, solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 antikoerper, solute carrier family 7 (amino acid transporter light chain, L system), member 8b antikoerper, SLC7A8 antikoerper, Slc7a8 antikoerper, slc7a8.L antikoerper, slc7a8 antikoerper, slc7a8b antikoerper

Hintergrund: Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.

Molekulargewicht: 58382

UniProt: Q9UHI5