This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Mouse Dnmt3l antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 383-417 amino acids from the C-terminal region of Mouse Dnmt3l.
TRDMT1
Reaktivität: Human
WB, ELISA, IHC, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
DNMT3L (TRDMT1)
(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
Andere Bezeichnung
Dnmt3l
Hintergrund
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases.