UBE2C Antikörper (C-Term)

Produktnummer ABIN6243143

Dieses Maus Monoklonal-Antikörper erkennt spezifisch UBE2C in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UBE2C Antikörper (C-Term) (ABIN6243143)

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UBE2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 2001CT211-37-61

Produktdetails anti-UBE2C Antikörper

Bindungsspezifität: C-Term

Homologie: B, Pr, M

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This UBE2C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 137~172 amino acids from the C-terminal region of human UBE2C.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Andere Bezeichnung: UBE2C

Hintergrund: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Molekulargewicht: 19652

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway