RGS19 Antikörper (AA 9-39)

Produktnummer ABIN6243053

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RGS19 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RGS19 Antikörper (AA 9-39) (ABIN6243053)

Target: RGS19 (Regulator of G-Protein Signalling 19 (RGS19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB11889

Produktdetails anti-RGS19 Antikörper

Bindungsspezifität: AA 9-39

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9~39 amino acids surrounding S24 of human RGS19.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu RGS19

Target: RGS19 (Regulator of G-Protein Signalling 19 (RGS19))

Andere Bezeichnung: RGS19

Hintergrund: RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

Molekulargewicht: 24636

NCBI Accession: NP_001034556, NP_005864

UniProt: P49795

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling