PRKAB1 Antikörper
Kurzübersicht für PRKAB1 Antikörper (ABIN6243028)
Target
Alle PRKAB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This PRKAB1 antibody is generated from a mouse immunized with a recombinant of human PRKAB1.
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Isotyp
- IgG1 kappa
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anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibody
PRKAB1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 201-270) antibodyPRKAB1 Reaktivität: Maus, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer182) antibodyPRKAB1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) antibodyPRKAB1 Reaktivität: Human, Maus WB, IHC, ICC, IP Wirt: Maus Monoclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (pSer181) antibodyPRKAB1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 13-242) antibodyPRKAB1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-80) antibodyPRKAB1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 4-34), (N-Term) antibodyPRKAB1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB3228 unconjugated
anti-Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1) (AA 1-270) antibodyPRKAB1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3H12-1A10 unconjugated
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
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Andere Bezeichnung
- PRKAB1
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Hintergrund
- Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
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Molekulargewicht
- 30382
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UniProt
- Q9Y478
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Pathways
- AMPK Signaling, Warburg Effekt
Target
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