NMNAT1 Antikörper (AA 171-201)
Kurzübersicht für NMNAT1 Antikörper (AA 171-201) (ABIN6242968)
Target
Alle NMNAT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 171-201
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Homologie
- B
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This NMNAT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 171-201 amino acids from human NMNAT1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000. WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
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Andere Bezeichnung
- NMNAT1
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Hintergrund
- Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.
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Molekulargewicht
- 31932
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UniProt
- Q9HAN9
Target
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