STUB1 Antikörper
Kurzübersicht für STUB1 Antikörper (ABIN6242870)
Target
Alle STUB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This STUB1 antibody is generated from a mouse immunized with a recombinant protein of human STUB1.
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Isotyp
- IgG1 kappa
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anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Schwein, Pferd, Affe, Huhn, Hamster, Avian, Cat, Esel, Ziege, Kaninchen, Schaf WB Wirt: Ziege Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodyVerified STUB1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibodySTUB1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231), (C-Term) antibodySTUB1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7393 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibodySTUB1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-48) antibodySTUB1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 236-263), (C-Term) antibodySTUB1 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB32217 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (N-Term) antibodySTUB1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:4000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
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Andere Bezeichnung
- STUB1
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Hintergrund
- E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF- BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation.
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Molekulargewicht
- 34856
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UniProt
- Q9UNE7
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Pathways
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
Target
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