SRY Antikörper (AA 81-112)

Produktnummer ABIN6242645

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SRY in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SRY Antikörper (AA 81-112) (ABIN6242645)

Target: SRY (Sex Determining Region Y (SRY))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB53826

Produktdetails anti-SRY Antikörper

Bindungsspezifität: AA 81-112

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SRY antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-112 amino acids from the Central region of human SRY.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SRY

Target: SRY (Sex Determining Region Y (SRY))

Andere Bezeichnung: SRY

Hintergrund: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Molekulargewicht: 23884

UniProt: Q05066