Lamin A/C Antikörper (AA 465-498)
Kurzübersicht für Lamin A/C Antikörper (AA 465-498) (ABIN6242430)
Target
Alle Lamin A/C (LMNA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 465-498
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This LMNA(Lamin-A/C) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 465-498 amino acids from the Central region of human LMNA(Lamin-A/C).
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:500. WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Lamin A/C (LMNA)
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Andere Bezeichnung
- LMNA(Lamin-A/C)
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Hintergrund
- Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.
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Molekulargewicht
- 74139
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UniProt
- P02545
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus
Target
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