BRD4 Antikörper (N-Term)

Produktnummer ABIN6242209

Dieses Anti-BRD4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRD4 in IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BRD4 Antikörper (N-Term) (ABIN6242209)

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3419

Produktdetails anti-BRD4 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BRD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human BRD4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-BRD4 Antikörper (ABIN6242209)

Gagnon, Joubert, Sénéchal, Fradet-Turcotte, Torre, Archambault: "Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4." in: Journal of virology, Vol. 83, Issue 9, pp. 4127-39, (2009) (PubMed).

Details zu BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Andere Bezeichnung: BRD4

Hintergrund: BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people.

Molekulargewicht: 152219

NCBI Accession: NP_055114, NP_490597

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom