INCENP
Reaktivität: Human
WB, IF, FACS
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
4 °C,-20 °C
Target
INCENP
(Inner Centromere Protein Antigens 135/155kDa (INCENP))
Andere Bezeichnung
INCENP
Hintergrund
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Probably acts through association with AURKB or AURKC. Seems to bind directly to microtubules. Controls the kinetochore localization of BUB1.