CBX3 Antikörper
Kurzübersicht für CBX3 Antikörper (ABIN6241538)
Target
Alle CBX3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Immunogen
- Recombinant Protein
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Applikationshinweise
- IP: 1:500. WB: 1:1000. IHC: 1:100. ICC: 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- 4 °C,-20 °C
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- CBX3 (Chromobox Homolog 3 (CBX3))
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Andere Bezeichnung
- HP1-gamma
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Hintergrund
- Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
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UniProt
- Q13185
Target
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