PAX7 Antikörper (AA 300-600) (CF®488A)

Produktnummer ABIN6189178

Der Maus Monoklonal Anti-PAX7-Antikörper wurde für WB, FACS, IF und IHC (fro) validiert. Er ist geeignet, PAX7 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio) und Huhn zu detektieren.

Kurzübersicht für PAX7 Antikörper (AA 300-600) (CF®488A) (ABIN6189178)

Target: PAX7 (Paired Box 7 (PAX7))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX7 Antikörper ist konjugiert mit CF®488A

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: PAX7-497

Produktdetails anti-PAX7 Antikörper (CF®488A)

Bindungsspezifität: AA 300-600

Verwendungszweck: Mouse Monoclonal anti-PAX7 (PAX7/497), CF488A Conjugate

Produktmerkmale: The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (aa300-600) of human PAX7 protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology (frozen) 0.5-1 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HeLa, Jurkat, A431, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Andere Bezeichnung: PAX7

Hintergrund: HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2

Molekulargewicht: 57 kDa

Gen-ID: 5081, 113253

UniProt: P23759