IFNA1 Antikörper (Biotin)

Produktnummer ABIN6186601

Der Maus Monoklonal Anti-IFNA1-Antikörper wurde für FACS und IF validiert. Er ist geeignet, IFNA1 in Proben von Human zu detektieren.

Kurzübersicht für IFNA1 Antikörper (Biotin) (ABIN6186601)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 2-52

Produktdetails anti-IFNA1 Antikörper (Biotin)

Verwendungszweck: Mouse Monoclonal anti-Interferon alpha-1 (2.52), Biotin Conjugate

Produktmerkmale: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified recombinant human IFN-alpha1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

Stimulated human peripheral blood mononuclear cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: Interferon alpha-1

Molekulargewicht: 16-27 kDa

Gen-ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signalweg, Hepatitis C