Transferrin Receptor Antikörper (CF®488A)

Produktnummer ABIN6185226

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Transferrin Receptor in FACS, WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Transferrin Receptor Antikörper (CF®488A) (ABIN6185226)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Klon: DF1513

Produktdetails anti-Transferrin Receptor Antikörper (CF®488A)

Verwendungszweck: Mouse Monoclonal anti-CD71 (DF1513), CF488A Conjugate

Produktmerkmale: This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: KG1 acute myeloid leukemia cell line

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1.0 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

Molekulargewicht: 85-95 kDa (monomer), 190 kDa (dimer)

Gen-ID: 7037, 529618

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis