Transferrin Receptor Antikörper (CF®594)

Produktnummer ABIN6185190

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Transferrin Receptor in FACS und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Transferrin Receptor Antikörper (CF®594) (ABIN6185190)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit CF®594

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 66IG10

Produktdetails anti-Transferrin Receptor Antikörper (CF®594)

Verwendungszweck: Mouse Monoclonal anti-CD71 (66IG10), CF594 Conjugate

Produktmerkmale: This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human thymocytes (T-cells)

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

Molekulargewicht: 85-95 kDa (monomer), 190 kDa (dimer)

Gen-ID: 7037, 529618

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis