CD235a/GYPA Antikörper
Kurzübersicht für CD235a/GYPA Antikörper (ABIN6184595)
Target
Alle CD235a/GYPA (GYPA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse Monoclonal anti-Glycophorin-A / CD235a (A63-B/C2), Purified, BSA-free
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Produktmerkmale
- This antibody recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Aufreinigung
- Purified
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Immunogen
- Human erythrocytes treated with neuraminidase
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Isotyp
- IgM kappa
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Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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Kommentare
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Erythrocytes
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS (no BSA, no azide)
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Konservierungsmittel
- Azide free
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- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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Andere Bezeichnung
- Glycophorin-A / CD235a
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Hintergrund
- Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha
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Molekulargewicht
- 39 kDa
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Gen-ID
- 2993, 2994
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UniProt
- P02724
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Pathways
- Maintenance of Protein Location
Target
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