UGT1A9 Antikörper (CF®488A)

Produktnummer ABIN6180742

Der Maus Monoklonal Anti-UGT1A9-Antikörper wurde für IF und FACS validiert. Er ist geeignet, UGT1A9 in Proben von Human zu detektieren.

Kurzübersicht für UGT1A9 Antikörper (CF®488A) (ABIN6180742)

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UGT1A9 Antikörper ist konjugiert mit CF®488A

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: UGT1A9-1229

Produktdetails anti-UGT1A9 Antikörper (CF®488A)

Verwendungszweck: Mouse Monoclonal anti-UGT1A9 (UDP glucuronosyltransferase-1 family, polypeptide A9) (UGT1A9/1229), CF488A Conjugate

Produktmerkmale: This antibody recognizes a protein of about 60 kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A synthetic peptide specific to human UGT1A9 protein

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HepG2 cells. Liver or Hepatocellular Carcinoma (HCC)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu UGT1A9

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Andere Bezeichnung: UGT1A9 (UDP glucuronosyltransferase-1 family, polypeptide A9)

Hintergrund: GNT1, HLUGP4, lugP4, UDP-glucuronosyltransferase 1-I, UDP-glucuronosyltransferase 1A9 (UGT1A9), UDPGT 1-9, UDPGT, UGT-1I, UGT1*9, UGT1-09, UGT1.9, Ugt1a9, UGT1I

Molekulargewicht: 60 kDa

Gen-ID: 54600, 554822

UniProt: O60656

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha