CTNNA1 Antikörper (CF®640R)

Produktnummer ABIN6178140

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CTNNA1 in WB, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CTNNA1 Antikörper (CF®640R) (ABIN6178140)

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTNNA1 Antikörper ist konjugiert mit CF®640R

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 1G5

Produktdetails anti-CTNNA1 Antikörper (CF®640R)

Verwendungszweck: Mouse Monoclonal anti-Catenin, alpha-1 (1G5), CF640R Conjugate

Produktmerkmale: This antibody recognizes a protein of 102 kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, ?-catenin forms a heterodimer with ?-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human alpha catenin fusion protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HeLa, A431 or MCF-7 Cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu CTNNA1

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Andere Bezeichnung: Catenin, alpha-1

Hintergrund: Alpha E-catenin, Cadherin-associated protein, CAP102, Catenin alpha-1, CTNNA1, Renal carcinoma antigen NY-REN-13

Molekulargewicht: 102 kDa

Gen-ID: 1495, 445981

UniProt: P35221

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location