beta-2 Microglobulin Antikörper (Biotin)

Produktnummer ABIN6175125

Dieses Maus Monoklonal-Antikörper erkennt spezifisch beta-2 Microglobulin in FACS und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für beta-2 Microglobulin Antikörper (Biotin) (ABIN6175125)

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta-2 Microglobulin Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 246-E9-E7|same as HLA-ABC-m2

Produktdetails anti-beta-2 Microglobulin Antikörper (Biotin)

Verwendungszweck: Mouse Monoclonal anti-Beta-2 Microglobulin (B2M) (246-E9.E7), Biotin Conjugate

Produktmerkmale: This antibody recognizes a protein of 12 kDa, identified asβ2-microglobulin.β2-microglobulin non-covalently associates with the 44 kDa chain to form the HLA Class I antigen complex. Human β2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human β2-microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of β2-microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection. Clone 246 E9.E7 is the same as HLA.ABC.m2. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Human PBLs from a T-cell acute lymphoblastic leukemia (T-ALL) patient

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Does not react with non-human primates, others not known

• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung: Beta-2 Microglobulin (B2M)

Hintergrund: B2M, Beta 2 microglobin, Beta 2 microglobulin, Beta chain of MHC class I molecules, Beta-2-microglobulin form pI 5.3, Hdcma22p

Molekulargewicht: 12 kDa

Gen-ID: 567, 534255

UniProt: P61769

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process