RBP1 Antikörper (CF®488A)

Produktnummer ABIN6172687

Produktdetails anti-RBP1 Antikörper (CF®488A)

Target: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Affe, Ziege, Schimpanse

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RBP1 Antikörper ist konjugiert mit CF®488A

Applikation: Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Verwendungszweck: Mouse Monoclonal anti-Retinol Binding Protein 1 (G4E4), CF488A Conjugate

Produktmerkmale: This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Retinol binding protein-1 purified from human plasma

Klon: G4E4

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology formalin-fixed 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

Hepatic or ovarian carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu RBP1

Target: RBP1 (Retinol Binding Protein 1, Cellular (RBP1))

Andere Bezeichnung: Retinol Binding Protein 1 (RBP1 Produkte)

Molekulargewicht: 21-25 kDa

Gen-ID: 5947, 5948, 5950

UniProt: P02753