MMP2 Antikörper (AA 444-575) (CF®594)
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- Target Alle MMP2 Antikörper anzeigen
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Bindungsspezifität
- AA 444-575
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MMP2 Antikörper ist konjugiert mit CF®594
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-MMP2 / Collagenase-Type-IV-A (MMP2/1501), CF594 Conjugate
- Produktmerkmale
- This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human MMP2 protein fragment (aa444-575) (exact sequence is proprietary)
- Klon
- MMP2-1501
- Isotyp
- IgG1
- Top Product
- Discover our top product MMP2 Primärantikörper
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- Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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U-138 MG or U-87 MG cells. Placenta
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Andere Bezeichnung
- MMP2 / Collagenase-Type-IV-A (MMP2 Produkte)
- Synonyme
- 2-MMP antikoerper, CG1794 antikoerper, DM2-MMP antikoerper, Dm2-MMP antikoerper, Dmel\\CG1794 antikoerper, MMP2 antikoerper, anon-WO0118547.84 antikoerper, dm-2MMP antikoerper, dmmp2 antikoerper, l(2)02353 antikoerper, mmp2 antikoerper, wu:fa99h12 antikoerper, wu:fk89d01 antikoerper, fgmmp-2 antikoerper, Mmp-2 antikoerper, LOC100135793 antikoerper, Clg4a antikoerper, GelA antikoerper, MMP-2 antikoerper, CLG4 antikoerper, CLG4A antikoerper, MMP-II antikoerper, MONA antikoerper, TBE-1 antikoerper, matrix metallopeptidase 2 antikoerper, Matrix metalloproteinase 2 antikoerper, matrix metalloproteinase 2 antikoerper, matrix metalloproteinase-2 antikoerper, MMP2 antikoerper, Mmp2 antikoerper, mmp2 antikoerper, LOC657982 antikoerper, LOC100135793 antikoerper
- Hintergrund
- 72 kD type IV collagenase|CLG4A|Collagenase Type 4 alpha|Collagenase type IV A|Gelatinase A|Gelatinase alpha|Gelatinase neutrophil|Matrix metalloproteinase-2|MMP2|MONA|Neutrophil gelatinase|PEX|TBE-1
- Molekulargewicht
- 72 kDa (Pro), 63 kDa (cleaved)
- Gen-ID
- 4313, 513617
- UniProt
- P08253
- Pathways
- Activation of Innate immune Response
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