MMP2 Antikörper (AA 444-575) (CF®405S)

Produktnummer ABIN6170346

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MMP2 in WB, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MMP2 Antikörper (AA 444-575) (CF®405S) (ABIN6170346)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP2 Antikörper ist konjugiert mit CF®405S

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: MMP2-1501

Produktdetails anti-MMP2 Antikörper (CF®405S)

Bindungsspezifität: AA 444-575

Verwendungszweck: Mouse Monoclonal anti-MMP2 / Collagenase-Type-IV-A (MMP2/1501), CF405S Conjugate

Produktmerkmale: This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human MMP2 protein fragment (aa444-575) (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

U-138 MG or U-87 MG cells. Placenta

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2 / Collagenase-Type-IV-A

Hintergrund: 72 kD type IV collagenase|CLG4A|Collagenase Type 4 alpha|Collagenase type IV A|Gelatinase A|Gelatinase alpha|Gelatinase neutrophil|Matrix metalloproteinase-2|MMP2|MONA|Neutrophil gelatinase|PEX|TBE-1

Molekulargewicht: 72 kDa (Pro), 63 kDa (cleaved)

Gen-ID: 4313, 513617

UniProt: P08253

Pathways: Activation of Innate immune Response