UCHL1 Antikörper (CF®488A)
Kurzübersicht für UCHL1 Antikörper (CF®488A) (ABIN6168257)
Target
Alle UCHL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
 - Mouse Monoclonal anti-PGP 9.5 / UCHL-1 (13C4), CF488A Conjugate
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Produktmerkmale
 - This MAb reacts with a protein of 20-30 kDa, identified as PGP 9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1). Initially, PGP 9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP 9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP 9.5 gene is believed to cause a form of Parkinson's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
 - Native UchL1 (PGP 9.5) protein from brain
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Isotyp
 - IgG2a kappa
 
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Applikationshinweise
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                        Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
 - Optimal dilution for a specific application should be determined by user
 
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Kommentare
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Cerebellum
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 100 μg/mL
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Buffer
 - PBS/0.1 % BSA/0.05 % azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Protect from light
 
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- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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Andere Bezeichnung
 - PGP 9.5 (UCHL-1)
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Molekulargewicht
 - 20-30 kDa
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Gen-ID
 - 7345, 518731
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UniProt
 - P09936
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Pathways
 - Feeding Behaviour
 
Target
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