LHCGR Antikörper (N-Term) (CF®405S)
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- Target Alle LHCGR Antikörper anzeigen
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LHCGR Antikörper ist konjugiert mit CF®405S
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR/1415), CF405S Conjugate
- Produktmerkmale
- This antibody recognizes a protein of 78-85 kDa, which is identified as luteinizing hormone/choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Purified recombinant N-terminal fragment of human LHCGR (exact sequence is proprietary)
- Klon
- LHCGR-1415
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product LHCGR Primärantikörper
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- Applikationshinweise
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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HepG2 or Jurkat cells. Ovary or Testis.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
- Andere Bezeichnung
- Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR Produkte)
- Synonyme
- HHG antikoerper, LCGR antikoerper, LGR2 antikoerper, LH/CG-R antikoerper, LH/CGR antikoerper, LHR antikoerper, LHRHR antikoerper, LSH-R antikoerper, ULG5 antikoerper, Gpcr19-rs1 antikoerper, LH-R antikoerper, Lhr antikoerper, LSHR antikoerper, lhr antikoerper, GTHR-II antikoerper, zfGTHR-II antikoerper, LHCGR antikoerper, LOC100222883 antikoerper, lh-r antikoerper, LOC100305044 antikoerper, luteinizing hormone/choriogonadotropin receptor antikoerper, luteinizing hormone/choriogonadotropin receptor L homeolog antikoerper, luteinizing hormone receptor antikoerper, LHCGR antikoerper, Lhcgr antikoerper, lhcgr antikoerper, lhcgr.L antikoerper, lhr antikoerper, LOC100305044 antikoerper
- Molekulargewicht
- 78-85 kDa
- Gen-ID
- 3973, 468490
- UniProt
- P22888
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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