beta-2 Microglobulin Antikörper (PE)
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- Target Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser beta-2 Microglobulin Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. Beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Size-Exclusion Chromatography.
- Immunogen
- Purified human beta2-microglobulin
- Klon
- B2M-01
- Isotyp
- IgG2a
- Top Product
- Discover our top product B2M Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Target
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- Andere Bezeichnung
- beta-2-Microglobulin (B2M Produkte)
- Hintergrund
- Beta2-microglobulin non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin
- Gen-ID
- 567
- NCBI Accession
- NP_004039
- UniProt
- P61769
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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