ADRP Antikörper (AA 249-376) (CF®568)
Kurzübersicht für ADRP Antikörper (AA 249-376) (CF®568) (ABIN6155709)
Target
Alle ADRP (PLIN2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 249-376
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Verwendungszweck
- Mouse Monoclonal anti-Adipophilin / Perilipin-2 (ADFP/1365), CF568 Conjugate
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Produktmerkmale
- This antibody recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant human Adipophilin protein fragment (aa249-376) (exact sequence is proprietary)
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
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Kommentare
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HepG2 or JAR cells. Liver, Adrenal gland or Cerebellum.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100 μg/mL
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Buffer
- PBS/0.1 % BSA/0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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- ADRP (PLIN2) (Perilipin 2 (PLIN2))
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Andere Bezeichnung
- Adipophilin / Perilipin-2
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Hintergrund
- Adipophilin, ADFP, Adipose differentiation-related protein (ADRP), Perilipin-2 (PLIN2)
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Molekulargewicht
- 48 kDa
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Gen-ID
- 123
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
Target
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