Aurora Kinase B Antikörper (AA 89-251) (CF®647)
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- Target Alle Aurora Kinase B (AURKB) Antikörper anzeigen
- Aurora Kinase B (AURKB)
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Bindungsspezifität
- AA 89-251
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Aurora Kinase B Antikörper ist konjugiert mit CF®647
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-Aurora-B (AURKB/1521), CF647 Conjugate
- Produktmerkmale
- This antibody recognizes a protein of 39 kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human Aurora B protein fragment (aa89-251) (exact sequence is proprietary)
- Klon
- AURKB-1521
- Isotyp
- IgG2b
- Top Product
- Discover our top product AURKB Primärantikörper
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- Applikationshinweise
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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HeLa cells. Tonsil, Placenta, Hodgkin s Lymphoma or Colon Carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- Aurora Kinase B (AURKB)
- Andere Bezeichnung
- Aurora-B (AURKB Produkte)
- Synonyme
- AIK2 antikoerper, AIM-1 antikoerper, AIM1 antikoerper, ARK2 antikoerper, AurB antikoerper, IPL1 antikoerper, PPP1R48 antikoerper, STK12 antikoerper, STK5 antikoerper, aurkb-sv1 antikoerper, aurkb-sv2 antikoerper, AIRK2 antikoerper, AL022959 antikoerper, Aik2 antikoerper, Aim1 antikoerper, Ark2 antikoerper, STK-1 antikoerper, Stk12 antikoerper, Stk5 antikoerper, Aur B antikoerper, Aurora B antikoerper, Aurora-B antikoerper, CG6620 antikoerper, DmAIRK2 antikoerper, DmAurB antikoerper, DmAuroraB antikoerper, Dmel\\CG6620 antikoerper, IAL antikoerper, IAL1 antikoerper, Ial antikoerper, aurB antikoerper, aurora B antikoerper, ARK-2 antikoerper, XAIRK2 antikoerper, aik2 antikoerper, aim-1 antikoerper, aim1 antikoerper, airk2 antikoerper, ark2 antikoerper, ipl1 antikoerper, stk12 antikoerper, stk5 antikoerper, CHUNP6896 antikoerper, fa09g06 antikoerper, stka antikoerper, wu:fa09g06 antikoerper, aurkb antikoerper, AIRK2-B antikoerper, XAIRK2-B antikoerper, aurkb-a antikoerper, aurkb-b antikoerper, xAurora-B-B antikoerper, aurora kinase B antikoerper, aurora B antikoerper, aurora kinase B S homeolog antikoerper, AURKB antikoerper, Aurkb antikoerper, aurB antikoerper, aurkb antikoerper, aurkb.S antikoerper
- Molekulargewicht
- 39 kDa
- Gen-ID
- 9212, 442658
- UniProt
- Q96GD4
- Pathways
- T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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