Dieser alpha 1 Adrenergic Receptor Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects Alpha-1A adrenergic receptor.
Kreuzreaktivität (Details)
Species reactivity (expected):The antibody is predicted to cross-react with the following species based on their respective sequence homologies: Mouse (100 %), Rat (100 %), Rabbit (100 %), Cow (100 %), Monkey (100 %). Cross-reactivity has not been experimentally confirmed at this time. Species reactivity (tested):Human
Aufreinigung
Immunoaffinity Chromatography
Immunogen
Synthetic peptide corresponding to a region within amino acids 206 and 270 of Human Alpha-1A adrenergic receptor
The alpha 1c- Adrenergic Receptor, also known as alpha 1a-adrenoceptor, is activated by epinephrine and norepinephrine. This receptor mediates calcium release upon ligand binding. The alpha 1-c adrenoceptor is one of three subtypes of alpha 1-adrenergic receptor (alpha 1 c/a, alpha 1b, and alpha 1d). The alpha 1c receptor couples to phospholipase C via a GTP-binding protein insensitive to pertussis toxin. Three isoforms are generated by alternative splicing. However, the corresponding isoforms of the protein have similar ligand-binding properties, effector coupling, and tissue distribution.Synonyms: ADRA1A, ADRA1C, Alpha 1A-adrenoceptor, Alpha 1A-adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c