TAG-72 / CA72.4 Antikörper (CF®488A)

Produktnummer ABIN6153855

Dieser Maus Monoklonal Antikörper erkennt spezifisch in FACS und IF. Er zeigt eine Reaktivität gegenüber Human, Hund, Rind (Kuh) und Ratte.

Kurzübersicht für TAG-72 / CA72.4 Antikörper (CF®488A) (ABIN6153855)

Target: TAG-72 / CA72.4

Reaktivität: Human, Hund, Rind (Kuh), Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: CF®488A

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: B72-3 CA72-733

Produktdetails

Verwendungszweck: Mouse Monoclonal anti-TAG-72 / CA72.4 (B72.3 + CA72/733), CF488A Conjugate

Produktmerkmale: This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the < a href="https://biotium.com/wp-content/uploads/2013/07/CF-dye-selection-guide.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: TAG-72 protein (B72.3 & CA72/733)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL

Kommentare:

Jurkat cells, Breast or lung carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Antigendetails

Target: TAG-72 / CA72.4

Hintergrund: CA72.4, Tumor associated glycoprotein 72

Molekulargewicht: 220 kDa

Gen-ID: 182875