CEACAM5 Antikörper

Produktnummer ABIN6151970

Produktdetails anti-CEACAM5 Antikörper

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Verwendungszweck: Mouse Monoclonal anti-CD66 / CEA (C66/195), Purified, BSA-free

Produktmerkmale: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: Recombinant full-length human CEA protein

Klon: C66-195

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL

Kommentare:

MCF7 or 293T cells. Colon carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Konservierungsmittel: Azide free

Details zu CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Andere Bezeichnung: CD66 (CEA) (CEACAM5 Produkte)

Synonyme: CD66e antikoerper, CEA antikoerper, CEACAM5 antikoerper, CEACAM antikoerper, 1600029H12Rik antikoerper, Psg30 antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 8 antikoerper, carcinoembryonic antigen gene family antikoerper, CEACAM5 antikoerper, Ceacam5 antikoerper, LOC100409241 antikoerper, Cea antikoerper

Hintergrund: Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)

Molekulargewicht: 80-200 kDa

Gen-ID: 1048, 634, 709196

UniProt: P06731