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ZBTB33 Antikörper (AA 523-672)

Dieses Anti-ZBTB33-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZBTB33 in WB und ChIP. Geeignet für Human.
Produktnummer ABIN6150379

Kurzübersicht für ZBTB33 Antikörper (AA 523-672) (ABIN6150379)

Target

Alle ZBTB33 Antikörper anzeigen
ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reaktivität

  • 24
  • 10
  • 7
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 21
  • 4
Kaninchen

Klonalität

  • 18
  • 7
Polyklonal

Konjugat

  • 21
  • 2
  • 1
  • 1
Dieser ZBTB33 Antikörper ist unkonjugiert

Applikation

  • 17
  • 12
  • 7
  • 5
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
  • Bindungsspezifität

    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 523-672

    Sequenz

    PCRYCEKVFP LAEYRTKHEI HHTGERRYQC LACGKSFINY QFMSSHIKSV HSQDPSGDSK LYRLHPCRSL QIRQYAYLSD RSSTIPAMKD DGIGYKVDTG KEPPVGTTTS TQNKPMTWED IFIQQENDSI FKQNVTDGST EFEFIIPESY

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 523-672 of human Kaiso/Kaiso/ZBTB33 (NP_006768.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:1000 - 1:2000,ChIP,1:50 - 1:200

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

    Andere Bezeichnung

    ZBTB33

    Hintergrund

    This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.,ZBTB33,ZNF-kaiso,ZNF348,Epigenetics & Nuclear Signaling,ZBTB33

    Molekulargewicht

    74 kDa

    Gen-ID

    10009

    UniProt

    Q86T24
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