WWOX Antikörper (AA 1-120)

Produktnummer ABIN6150272

Der Kaninchen Polyklonal Anti-WWOX-Antikörper wurde für WB und IF validiert. Er ist geeignet, WWOX in Proben von Human zu detektieren.

Kurzübersicht für WWOX Antikörper (AA 1-120) (ABIN6150272)

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-WWOX Antikörper

Bindungsspezifität: AA 1-120

Sequenz: MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human WWOX (NP_057457.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WWOX

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Andere Bezeichnung: WWOX

Hintergrund: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.,WWOX,D16S432E,EIEE28,FOR,FRA16D,HHCMA56,PRO0128,SCAR12,SDR41C1,WOX1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,WWOX

Molekulargewicht: 4 kDa/21 kDa/23 kDa/26 kDa/35 kDa/41 kDa/46 kDa

Gen-ID: 51741

UniProt: Q9NZC7