TSC1 Antikörper (AA 550-650)
Kurzübersicht für TSC1 Antikörper (AA 550-650) (ABIN6149609)
Target
Alle TSC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 550-650
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Sequenz
- QAFTPIDLPC GSADESPAGD RECQTSLETS IFTPSPCKIP PPTRVGFGSG QPPPYDHLFE VALPKTAHHF VIRKTEELLK KAKGNTEEDG VPSTSPMEVL D
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TSC1 (NP_000359.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
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: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
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- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Andere Bezeichnung
- TSC1
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Hintergrund
- This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.,TSC1,LAM,TSC,hamartin,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Obesity,Akt downstream targets,Regulators,TSC1
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Molekulargewicht
- 124 kDa/129 kDa
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Gen-ID
- 7248
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UniProt
- Q92574
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Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
Target
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