TINF2 Antikörper (AA 202-451)
Kurzübersicht für TINF2 Antikörper (AA 202-451) (ABIN6149187)
Target
Alle TINF2 (TIN2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 202-451
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Sequenz
- ECSVTDSVNL AEPMEQNPPQ QQRLALHNPL PKAKPGTHLP QGPSSRTHPE PLAGRHFNLA PLGRRRVQSQ WASTRGGHKE RPTVMLFPFR NLGSPTQVIS KPESKEEHAI YTADLAMGTR AASTGKSKSP CQTLGGRALK ENPVDLPATE QKENCLDCYM DPLRLSLLPP RARKPVCPPS LCSSVITIGD LVLDSDEEEN GQGEGKESLE NYQKTKFDTL IPTLCEYLPP SGHGAIPVSS CDCRDSSRPL
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 202-451 of human TIN2/TIN2/TINF2 (NP_001092744.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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Andere Bezeichnung
- TINF2
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Hintergrund
- This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.,TINF2,DKCA3,TIN2,Epigenetics & Nuclear Signaling,TINF2
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Molekulargewicht
- 15 kDa/39 kDa/50 kDa
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Gen-ID
- 26277
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UniProt
- Q9BSI4
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Pathways
- Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
Target
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