SYNPO2 Antikörper (AA 1-300)

Produktnummer ABIN6148777

Dieses Anti-SYNPO2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SYNPO2 in WB. Geeignet für Human.

Kurzübersicht für SYNPO2 Antikörper (AA 1-300) (ABIN6148777)

Target: SYNPO2 (Synaptopodin 2 (SYNPO2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNPO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYNPO2 Antikörper

Bindungsspezifität: AA 1-300

Sequenz: MGTGDFICIS MTGGAPWGFR LQGGKEQKQP LQVAKIRNQS KASGSGLCEG DEVVSINGNP CADLTYPEVI KLMESITDSL QMLIKRPSSG ISEALISENE NKNLEHLTHG GYVESTTLQI RPATKTQCTE FFLAPVKTEV PLAENQRSGP DCAGSLKEET GPSYQRAPQM PDSQRGRVAE ELILREKVEA VQPGPVVELQ LSLSQERHKG ASGPLVALPG AEKSKSPDPD PNLSHDRIVH INSIPTNEKA DPFLRSSKII QISSGRELRV IQESEAGDAG LPRVEVILDC SDRQKTEGCR

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SYNPO2 (NP_597734.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SYNPO2

Target: SYNPO2 (Synaptopodin 2 (SYNPO2))

Andere Bezeichnung: SYNPO2

Hintergrund: Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner. At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes (By similarity. Involved in regulation of cell migration. May be a tumor suppressor.,SYNPO2,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SYNPO2

Molekulargewicht: 74 kDa/117 kDa/119 kDa/133 kDa/136 kDa

Gen-ID: 171024

UniProt: Q9UMS6