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SYNPO2 Antikörper (N-Term)

SYNPO2 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783775
  • Target Alle SYNPO2 Antikörper anzeigen
    SYNPO2 (Synaptopodin 2 (SYNPO2))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SYNPO2 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects SYNPO2 at N-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    20 amino acid peptide near the amino terminus of human SYNPO2
    Top Product
    Discover our top product SYNPO2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    SYNPO2 (Synaptopodin 2 (SYNPO2))
    Andere Bezeichnung
    SYNPO2 (SYNPO2 Produkte)
    Synonyme
    SYNOP2 antikoerper, RGD1564779 antikoerper, 1110069I04Rik antikoerper, 2310068J10Rik antikoerper, 9530006G20Rik antikoerper, AI848603 antikoerper, Myo antikoerper, synaptopodin 2 antikoerper, synaptopodin-2 antikoerper, SYNPO2 antikoerper, LOC100484043 antikoerper, Synpo2 antikoerper
    Hintergrund
    SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.
    Gen-ID
    171024
    NCBI Accession
    NP_001122405
    UniProt
    Q9UMS6
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